A case report and review of the literature: ciprofloxacin resistant Salmonella enterica serovar Typhi in India.
نویسندگان
چکیده
BACKGROUND Enteric fever is a major public health problem in India. The current treatment of choice is the fluoroquinolones. METHODS The minimum inhibitory concentration (MIC) of ciprofloxacin was determined by E-test, HIMEDIA HiComb MIC test and agar dilution. RESULTS An isolate of Salmonella enterica serovar Typhi (S. Typhi) from a case of enteric fever gave a ciprofloxacin MIC of 64 microg/ml. CONCLUSIONS To our knowledge there have been no reports of such high-level resistance to ciprofloxacin in S. Typhi from southern India. HIMEDIA HiComb MIC test method is an alternative to the E-test. Ciprofloxacin resistant typhoid fever responds to treatment with ceftriaxone.
منابع مشابه
Nalidixic acid-resistant Salmonella enterica serotype Typhi presenting as a primary psoas abscess: case report and review of the literature.
We report an unusual case of Salmonella enterica serotype Typhi presenting as a primary psoas abscess. The isolate tested susceptible to ciprofloxacin but resistant to nalidixic acid in vitro, a pattern associated with fluoroquinolone therapeutic failures. We review the literature for serovar Typhi psoas abscess in the absence of bacteremia and discuss the importance of identifying isolates wit...
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Enteric fever prevails as a major public health problem despite the use of antimicrobials due to the emergence of drug resistance. The present study was undertaken to find out the antimicrobial susceptibility pattern of Salmonella isolates from our region. Antimicrobial susceptibility testing for six drugs chloramphenicol (30μg), amoxicillin (10μg), cotrimoxazole (1.25/23.75μg), nalidixic acid ...
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In developed countries, typhoid fever is often associated with persons who travel to endemic areas or immigrate from them. Typhoid fever is a systemic infection caused by Salmonella enterica serovar Typhi. Because of the emergence of antimicrobial resistance to standard first-line drugs, fluoroquinolones are the drugs of choice. Resistance to ciprofloxacin by this Salmonella serovar represents ...
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ورودعنوان ژورنال:
- Journal of infection in developing countries
دوره 2 4 شماره
صفحات -
تاریخ انتشار 2008